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Visit my website for a full list of videos. Enjoy. drkevinmangum.com/youtube-pathology-videos What is Anaplasia? What is Dysplasia? What are the differences between Anaplasia and Dysplasia? Dysplasia, a term used to describe disorderly but non-neoplastic proliferation. Dysplasia is encountered principally in the epithelia. It is a loss in the uniformity of individual cells and in their architec...

Visit my website for a full list of videos. Enjoy. drkevinmangum.com/youtube-pathology-videos What is Differentiation and Anaplasia? How to tell a benign and malignant tumor apart? Differentiation and anaplasia refer only to the parenchymal cells that constitute the transformed elements of neoplasms. The differentiation of parenchymal cells refers to the extent to which they resemble their norm...

Visit my website for a full list of videos. Enjoy. drkevinmangum.com/youtube-pathology-videos In general, benign tumors are designated by attaching the suffix -oma to the cell type from which the tumor arises. A benign tumor arising in fibrous tissue is a fibroma; a benign cartilaginous tumor is a chondroma. The nomenclature of benign epithelial tumors is more complex. They are classified somet...

Visit my website for a full list of videos. Enjoy. drkevinmangum.com/youtube-pathology-videos A tumor is said to be benign when its microscopic and gross characteristics are considered to be relatively innocent, implying that it will remain localized, it cannot spread to other sites, and is amenable to local surgical removal; the patient generally survives. It should be noted, however, that ben...

Visit my website for a full list of videos. Enjoy. drkevinmangum.com/youtube-pathology-videos Neoplasia literally means "new growth." A neoplasm, as defined by Willis, is "an abnormal mass of tissue the growth of which exceeds and is uncoordinated with that of the normal tissues and persists in the same excessive manner after the cessation of the stimuli which evoked the change." Fundamental to...

Visit my website for a full list of videos. Enjoy. www.drkevinmangum.com What is the Autonomic Nervous System? What is the Parasympathetic nervous system or the parasympathetic division of the Autonomic nervous system? The parasympathetic division comprises a cranial portion, emanating from the brainstem, and a sacral portion, originating in the intermediate gray zone of the sacral spinal cord....

Visit my website for a full list of videos. Enjoy. www.drkevinmangum.com What is the Autonomic Nervous System? What is the Sympathetic nervous system or the Sympathetic division of the Autonomic Nervous System? Preganglionic neurons of the sympathetic division originate in the intermediolateral horn of the thoracic (T1 to T12) and upper lumbar (L1 to L3) spinal cord. The preganglionic axons exi...

Visit my website for a full list of videos. Enjoy. www.drkevinmangum.com What is the Autonomic Nervous System? The ANS is classically divided into two subsystems: the parasympathetic nervous system (PSNS) and sympathetic nervous system (SNS), which operate independently in some functions and interact co-operatively in others. In many cases the two have "opposite" actions where one activates a p...

Visit my website for a full list of videos. Enjoy. drkevinmangum.com/youtube-pathology-videos Severe combined immunodeficiency (SCID) represents a constellation of genetically distinct syndromes with the common feature of defects in both humoral and cell-mediated immune responses. Affected infants are susceptible to severe recurrent infections by a wide array of pathogens, including bacteria, v...

Visit my website for a full list of videos. Enjoy. drkevinmangum.com/youtube-pathology-videos Common Variable Immunodeficiency is a heterogeneous group of disorders characterized by hypogammaglobulinemia, impaired antibody responses to infection (or vaccination), and increased susceptibility to infections. Isolated IgA Deficiency is the Most common of all the primary immune deficiency diseases ...

Visit my website for a full list of videos. Enjoy. www.drkevinmangum.com The term half maximal effective concentration (EC50) refers to the concentration of a drug, antibody or toxicant which induces a response halfway between the baseline and maximum after a specified exposure time. It is commonly used as a measure of drug's potency. Kd (the equilibrium dissociation constant) represents the co...

Visit my website for a full list of videos. Enjoy. www.drkevinmangum.com Pharmacokinetics is a branch of pharmacology dedicated to the determination of the fate of substances administered externally to a living organism. It attempts to discover the fate of a drug from the moment that it is administered up to the point at which it is completely eliminated from the body. Pharmacokinetics describe...

Visit my website for a full list of videos. Enjoy. www.drkevinmangum.com Half Maximal Effective Concentration (EC50) = concentration of a drug, antibody or toxicant which induces a response halfway between the baseline and maximum after a specified exposure time Median Lethal Dose (LD50) = a dose of a toxin, radiation, or pathogen required to kill half the members of a tested population after a...

Visit my website for a full list of videos. Enjoy. www.drkevinmangum.com Pharmacology: the study of substances that interact with living systems through chemical processes, especially by binding to regulatory molecules and activating or inhibiting normal body processes. A drug: may be defined as any substance that brings about a change in biologic function through its chemical actions. Katzung,...

105P- What is X-Linked Agammaglobulinemia, XLA, or Bruton Disease?

104P - Introduction to primary and secondary Immune deficiency diseases

103P Polymyositis, Dermatomyositis, Inclusion body myositis, Mixed Connective Tissue Disease

102P Systemic sclerosis, commonly called scleroderma, CREST syndrome, Raynaud phenomenon

101P - What is Sjögren Syndrome?

100P - Enteropathic Arthropathy

99P Psoriatic Arthritis; "pencil in cup" deformity

97P What is Ankylosing Spondylitis?

98P - What is Reiter's Syndrome or Reactive arthritis?

96P Introduction to the Seronegative Spondyloarthropathies

95P What is Juvenile Rheumatoid Arthritis, JRA, JIA

94P Pathogenesis of Rheumatoid Arthritis, RA

93P What is Rheumatoid Arthritis, RA, morphology, prevalence, pannus, Rheumatoid nodules

92P Morphology of Systemic lupus erythematosus, SLE, part 3

91P Morphology of Systemic lupus erythematosus, SLE, part 2, glomerular disease in SLE